The global Opioid Addiction and Dependence Market is projected to experience significant revenue growth over the forecast period. The increasing prevalence of opioid addiction and dependency, which is a leading cause of death, is driving this growth, particularly due to prescription drug overdoses. In 2016, it was estimated that 2.1 million Americans had opioid use disorder, according to the CDC. Opioid drugs such as Oxycodone, codeine, hydrocodone, morphine, and fentanyl are the most commonly abused substances in this category. The market is further expected to expand due to the severe long-term effects of opioid use, such as physical dependency and the emergence of withdrawal symptoms upon rapid discontinuation. The rising number of opioid addiction cases each year poses a significant public health concern.
The term "opioids" encompasses substances that can interact with opioid receptors in the brain, including substances derived from poppy seeds, as well as semi-synthetic and synthetic substances with similar properties. Opioids like morphine, fentanyl, and tramadol are frequently prescribed for pain relief. Opioid addiction is a chronic condition that has detrimental effects on an individual's health, relationships, and finances. A key characteristic of opioid addiction is an intense and compulsive urge to consume opioid medications, even when they are no longer medically necessary. Even when opioids are prescribed and taken correctly, there is a substantial risk of developing an addiction due to mishandling or diversion of prescription opioids. Opioid addiction can lead to life-threatening health issues, including the risk of overdose. High doses of opioids can slow or stop breathing, resulting in unconsciousness and potentially death.
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Drivers: The increasing number of individuals dependent on drugs is expected to fuel the global market for opioid dependence treatment. Every year, around 2 million Americans and an estimated 15 million individuals worldwide are affected by heroin and prescription opiate abuse. Opioid abuse and addiction are on the rise due to the prevalence of severe and chronic diseases, such as cancer, cardiovascular disease, injuries, and other conditions, which often require the use of painkillers, primarily opioids, for management. However, the use of these drugs can lead to addiction, especially when patients develop a dependency on them and experience withdrawal symptoms upon abrupt discontinuation.
For example, a WHO report states that globally, drug use accounts for approximately 0.5 million deaths, with over 70% of these deaths attributed to opioids and more than 30% caused by overdose in 2020. According to the Centers for Disease Control and Prevention, opioids were involved in 49,860 overdose deaths in the United States in 2019, accounting for 70.6% of all drug overdose deaths.
Furthermore, market growth is driven by the increased use of synthetic opioids such as fentanyl, a potent synthetic opioid used for anesthesia and pain management. The number of opioid addicts using illicitly produced and grown heroin is also expanding. According to the WHO, approximately 275 million people, or 5.5% of the global population between the ages of 15 and 64, have used drugs at least once, with around 62 million of them being opioid users. In 2019, about 36.3 million people experienced drug use problems, which will contribute to market growth over the forecast period.
Restraints: The lack of awareness, high treatment costs, and limited treatment options for opioid addiction or dependency are anticipated to hinder market expansion. One primary factor projected to impede the global market's growth during the forecast period is the negative effects that medications used for treating opioid addiction can have. These medications often result in side effects such as nausea, vomiting, abdominal cramps, diarrhea, respiratory issues, bone or joint pain, muscle aches, and constipation.
Opportunities: The rise of the Opioid Overdose market has been positively influenced by increased awareness and collaborative efforts of various organizations and groups working to prevent opioid addiction and dependency. Government initiatives to combat drug and opioid addiction have created significant opportunities for the opioid addiction treatment industry. The Centers for Disease Control and Prevention (CDC), for instance, is dedicated to addressing the opioid overdose crisis by partnering with states, localities, medical professionals, community-based organizations, and the public to increase knowledge, resources, and expertise. The CDC's efforts include identifying outbreaks, collecting data, responding to overdoses, and providing care to affected communities.
Geographic Market Scenario: Largest Market Share: The North American market is expected to hold the highest revenue share during the forecast period. This can be attributed to the increasing use of synthetic opioids, particularly fentanyl and its analogues, in the United States. Every year, over 2 million Americans and an estimated 15 million individuals globally are affected by the misuse of prescription opioids and heroin. Opioid overdoses resulted in over 20,000 fatalities in the United States in 2016, with 13,000 lives lost due to heroin overdoses. The majority of drug overdose deaths among Americans under the age of 50 are now caused by opioids, accounting for over half of all drug overdose fatalities. The market is expected to be driven by the growing number of drug addicts in North America and the increasing number of consumers, including misguided youth, engaging in drug misuse and dependency.
Fastest Growing Region: The Asia Pacific region is projected to experience the fastest growth rate during the forecast period, followed by Europe. For instance, a study published in the National Center for Biotechnology Information reported that India has twice the rate of illicit opiate use compared to the rest of the world. It is estimated that India had 4 million opioid users and 1 million opioid-dependent individuals in 2018.
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Key Market Trends and Innovations: One of the anticipated trends in the global market for treating opioid addiction is the increasing use of buprenorphine patches as a successful treatment for opioid use disorder. Buprenorphine patches are considered an innovative approach to treating opioid use disorder. Transdermal patches offer a more convenient method of drug delivery that effectively reduces pain and can be self-administered by the patient, unlike conventional therapy modalities such as injections. These buprenorphine patches also have the potential to serve as an alternative treatment for individuals in need of immediate care for opioid use disorder.
Organic and Inorganic Strategies Adopted: Key players in the market include Opiant Pharmaceuticals, Pear Therapeutics, Foresee Pharma, Indivior Plc., Alkermes, Orexo AB, Titan Pharmaceuticals, Inc., BioDelivery Sciences International Inc., Collegium Pharmaceutical, Inc., Viatris Inc., Pfizer, Inc., Hikma Pharmaceuticals Plc., and start-ups like Pannex Therapeutics.
What Our Report Provides and Why Our Offering Is Better: Our report offers historical data, forecasts, and revenue growth at a global, regional, and country level. It provides analysis, industry trends, and consumption patterns for each region, major country, and segment from 2019 to 2030. The report includes industry analysis, competitive landscape, company financials, and impact analysis, as well as detailed information on market strategies, segment revenue, and revenue share contribution for each regional and country market.
Product Type Outlook (Revenue, USD Billion; 2019-2030):
- Solid Dosage Form: Tablet, Capsule, Patch
- Liquid Dosage Form: Injectable
Route of Administration Outlook (Revenue, USD Billion; 2019-2030):
- Oral
- Parenteral
- Topical
Drug Class Outlook (Revenue, USD Billion; 2019-2030):
- Opioid Agonists
- Partial Agonists
- Opioid Antagonists
- Alpha-2-Adrenergic Agonists
End-Use Outlook (Revenue, USD Billion; 2019-2030):
- Hospitals
- Home care settings
- Clinics
Distribution Channel Outlook (Revenue, USD Billion; 2019-2030):
- Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
Regional Outlook (Revenue, USD Billion; 2019-2030):
- North America: U.S., Canada, Mexico
- Europe: Germany, UK, France, Italy, Spain, Benelux, Rest of Europe
- Asia Pacific: China, India, Japan, South Korea, Rest of Asia Pacific
- Latin America: Brazil, Rest of Latin America
- Middle East Africa: Saudi Arabia, UAE, South Africa, Rest of Middle East Africa
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